Search results for "Research process"
showing 10 items of 24 documents
Off-Target-Based Design of Selective HIV-1 PROTEASE Inhibitors
2021
The approval of the first HIV-1 protease inhibitors (HIV-1 PRIs) marked a fundamental step in the control of AIDS, and this class of agents still represents the mainstay therapy for this illness. Despite the undisputed benefits, the necessary lifelong treatment led to numerous severe side-effects (metabolic syndrome, hepatotoxicity, diabetes, etc.). The HIV-1 PRIs are capable of interacting with “secondary” targets (off-targets) characterized by different biological activities from that of HIV-1 protease. In this scenario, the in-silico techniques undoubtedly contributed to the design of new small molecules with well-fitting selectivity against the main target, analyzing possible undesirabl…
Assimilation of problematic experiences in Brief Strategic Therapy: Olivia and her fear of dying /La asimilación de experiencias problemáticas en la …
2016
AbstractIn this research process, Stiles’ assimilation of problematic experiences scale is used to study Olivia’s process of change. The objectives of this study are: first, to describe Olivia’s therapeutically successful assimilation of the problematic experience of fear of dying, treated with brief strategic therapy; and second, to study how that pattern of assimilation unfolded. We can conclude that Olivia assimilated her problematic experience of fear of dying by following a fluctuating and irregular pattern.
The child diary as a research tool
2012
The aim of this article is to introduce the use of the child diary as a method in daily diary research. By describing the research process and detailing its structure, a child diary, a structured booklet in which children's parents and day-care personnel (N = 54 children) reported their observations, was evaluated. The participants reported the use of the diary to be an interesting but time-consuming experience. The main ethical challenges were related to power positions, confidentiality, consequences and motivation. With respect to adults’ observations of children's emotions, the results indicated that the child diary is valuable in providing information about individual differences and da…
Learning Research Methods and Processes via Sharing Experience in a BLOG
2006
The goal is to increase knowledge about different research methods that have been employed in the information technology field by supporting the information exchange, collaboration, and cooperation between researchers. Well-designed, well-told stories can help others learn from past situations to respond more effectively in future situation. A blog is presented where PhD students and researchers are invited to collaborate by providing their stories, reading and commenting existing stories. This infrastructure allows researchers and PhD students to write the contents posing questions and finding answers on the relationship between research process and research results.
On the rhetoric and relevance of IS research paradigms: a conceptual framework and some propositions
2003
This paper discusses the relevance of IS research with respect to the rhetoric associated with three IS research paradigms in use - positivism, constructivism/interpretivism and critical research. The discussion is framed in terms of the following dimensions: ontological, epistemological and methodological assumptions, relationship between theory and practice, and the role of the researcher in the research process. Based on this discussion, the authors propose a theoretical framework to study the relationship of the espoused assumptions of a researcher's perspective with the degree of relevance of their knowledge claims to various stakeholders. In conclusion, some key propositions are eluci…
Bodily Flashes of Dancing Women: Dance as a Method of Inquiry
2003
In May 1997 I was in Nicaragua researching a dance ritual known as May Pole. The act of dancing itself became a method of inquiry in my research process. This article concentrates on the interaction of two dancing women, Evelyn and me. My dance experience has acquired different interpretations in relation to time and context as I have reflected on it. I also enrich this experience with other dance experiences to explore my dancing body in its different forms. This hermeneutical starting point creates the conditions for trusting my instrument, my body, as a source of bodily knowledge.
Cuerpos diversos, Tetas Diversas. Acción artística para sensibilizar en igualdad de género y diversidad sexual a través de la cerámica
2021
En este fotoensayo, presentamos el desarrollo de la acción
 Tetas Diversas
 , realizada durante el mes de octubre de 2020 con alumnado del Grado de Maestro/a en Educación Primaria de la Facultad de Magisterio de la Universitat de València. Esta acción forma parte de un proceso de investigación para analizar y valorar el papel de las acciones artísticas en los procesos de sensibilización respecto a cuestiones de identidad de género y diversidad sexual. La experiencia consiste en la reflexión sobre la diversidad de nuestros cuerpos desde una mirada ecofeminista para reivindicar la necesidad de una institución más humanizada, naturalizada, igualitaria, respetuosa con la diversidad e …
The Ph.D.-candidate as an information literate resource: developing research support and information literacy skills in an informal setting
2013
Published version of an article in the journal Liber Quarterly, Open Access This article aims to suggest a new way of developing research support for PhD-candidates. Previous research on the field of research support is greatly focused on librarians’ competencies and how to assist researchers with what they lack in information literacy (IL) skills. There is little focus on collaboration with researchers to achieve a mutual learning outcome in regard to developing research support and IL skills. A socio-cultural view on IL indicates that IL skills are developed in a context, and therefore are situated. A high level of IL in one situation could be regarded as insufficient in another. Therefor…
“SEE, HEAR, REMAIN SILENT AND… BORED” IN THE FIELDWORK OF A PRISON: AN AUTOETHNOGRAFIC STORY
2017
Como modalidad de investigación narrativa, la autoetnografía enfatiza la parte más personal del proceso de investigación. En este artículo, el relato autoetnográfico se utiliza para reflexionar sobre el trabajo de campo de un estudio etnográfico previo desarrollado en el polideportivo de una prisión de máxima seguridad española. Los datos recogidos en aquella ocasión han sido reexaminados ahora para explicitar críticamente los pasos dados. De este modo, se ponen de manifiesto tanto los dilemas éticos enfrentados, las complejas relaciones sociales que el proceso de investigación encerró, así como la falibilidad de las decisiones tomadas.
PELA-USAL: A Methodological Tool for the Study of Elites
2020
This introductory chapter presents the Parliamentary Elites of Latin America (PELA-USAL) project, which has conducted interviews with Latin American legislators in the lower chambers of political representation for more than 20 years. The following emphasizes the PELA-USAL project’s methodology, as well as its most important inputs and future challenges. Based on the experience of researchers from the project, our aim here is to re-think several issues (such as data mining) that arise during the research process, taking into account the wealth of available information (after two decades of development) and the particularities that parliamentary elites present as an object of study. First we…